The Effects Of Sleep Deprivation On Insulin Resistance And...

The Effects of Sleep Deprivation on Insulin Resistance and Type 2 Diabetes A Meta-Analysis Dalal Mazraeh Saint James School of Medicine Preceptor: Maja Delibasic, M.D. ABSTRACT Sleep deprivation and sleep restriction leads to insulin resistance and the development of type 2 diabetes. To study whether shortened sleep and sleep deprivation affects insulin resistance and glucose intolerance, we developed a meta-analysis of 7 studies that research this topic. The studies included had 92,176 men and women participants with no previous diagnoses of diabetes, with follow-up range of 2-15 years. Of the total participants, 3,206 cases of type 2 diabetes were reported in the follow up period . In pooled analyses, sleep deprivation showed a significant relationship to increased insulin resistance and development of type 2 diabetes. The follow-up period also showed a progressive increase in diabetes. For short duration of sleep (≠¤5–6 h/night), the RR was 1.66 (95% CI 1.54-1.78, P = 0.001 and heterogeneity P = 0.012). Sleep deprivation may be a significant and an independent factor that may lead to insulin resistance, glucose intolerance and symptomatic d iabetes. INTRODUCTION It has been scientifically proven that sleep is a crucial biological task that our body performs to maintain optimal functional capacity(Xu, Q. 2010). According to data collected by National sleep foundation short sleep deprivation is linked with many side effects, such as, increased risk ofShow MoreRelatedSleep Deprivation And Its Effects1738 Words   |  7 PagesSleep is a major component of human life, taking up almost a third of an individual’s lifetime and allowing the brain to process an individual’s experiences, thoughts, and memories. Proper sleep is vital to maintaining good health, as it is associated with maintenance of many of the body’s processes such as metabolism and disease prevention. 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